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NANOFLOW DELIVERY01INTEGRATED NANOLC–MS INTERFACE
Control the interface.
Preserve the workflow.
An integrated interface architecture for the complete transition from NanoLC fluid delivery to controlled nanospray ion transfer—combining a tool-free fluid path, an enclosed quartz emitter and instrumented source control.
CONTROLLED NANOSPRAY INTERFACECONCEPT CONFIGURATIONIONAE / NANOLC–MS
02NANOLC–MS INTERFACE ARCHITECTURE
One engineered pathway.
Four controlled transitions.
Fluid delivery, emitter positioning, nanospray formation and ion transfer are treated as one coordinated interface rather than isolated accessories.
NANOFLOW DELIVERY↗
QUARTZ EMITTER↗
NANOSPRAY CONTROL◎
MSION TRANSFER03INTERFACE COMPONENTS
Purpose-built for every interface transition.
TOOL–FREEFINGERTIGHT CONNECTION
02 / FLUIDICS04FLUIDICS / IONITUBE
TOOL–FREEFINGERTIGHT CONNECTION
Tool-free connection.
A continuous NanoLC fluid path.
ioniTube provides the dedicated fluidic route between the NanoLC outlet and the enclosed ioniTip emitter. Preassembled fingertight fittings allow direct hand installation while maintaining a clearly defined, zero-dead-volume connection architecture.
PRODUCT ADVANTAGES
Tool-free installation
Fingertight connection by hand—no wrench or separate installation tool required.
Zero-dead-volume architecture
A defined internal connection path designed without unnecessary interconnect volume.
Preassembled fluidic interface
Fittings are integrated with the tubing to simplify installation and component changeover.
Direct NanoLC-to-emitter routing
A dedicated clear fluid path connects the LC outlet directly to the protected emitter environment.
05EMITTER / IONITIP
A protected quartz emitter
for controlled nanospray operation.
ioniTip is a dedicated nano spray emitter column installed completely inside ioniFlux. The quartz tip is positioned within the source environment for controlled alignment, thermal conditioning and direct optical observation—without protruding beyond the housing.
PRODUCT ADVANTAGES
Quartz nanospray emitter
A fine glass emitter geometry dedicated to nanospray formation at the column outlet.
Fully enclosed installation
The complete tip remains within the ioniFlux housing for protection during setup and operation.
Controlled source environment
The installed emitter is supported by the positioning and thermal-control functions of ioniFlux.
Direct optical observation
Tip alignment and spray state can be inspected through the illuminated macro-camera system.
03 / EMITTER06IONIFLUX / INSTRUMENTED NANOESI SOURCE
An instrumented environment
for NanoESI control.
ioniFlux integrates mechanical positioning, thermal conditioning, optical observation and protected source handling around the enclosed ioniTip emitter.
Coaxial emitter positioning
An internal linear guide supports controlled forward and retract movement toward the MS ion-transfer interface.
Integrated thermal zone
The emitter is operated within a managed heating environment with touchscreen status and control.
Macro imaging with illumination
An integrated camera and dedicated light source provide direct observation of the emitter and nanospray state.
Protected tip handling
A defined safe position and long-press screen lock help protect the emitter from unintended movement.
Retractable observation access
The sliding transparent window provides visual access while retracting into the housing when the interface is opened.
Instrument-side docking
The open source end is arranged for coaxial alignment with a confirmed MS ion-transfer interface configuration.
07APPLICATION WORKFLOWS
Designed for controlled
NanoLC–MS interfacing.
Proteomics
Nano-flow peptide separation coupled to mass spectrometry
Metabolomics
Low-flow chromatographic separation and MS transfer workflows
Biopharmaceutical analysis
NanoLC–MS characterization workflows for biotherapeutic samples
08THERMO COMPATIBILITY
Interface configurations for confirmed
Thermo Scientific platforms.
Compatibility documentation will identify validated instrument and interface configurations without implying universal model support.